2025-06-25
Several prescription weight loss medications are approved by the FDA for long-term use. These include Contrave (bupropion-naltrexone), Saxenda (liraglutide), Qsymia (phentermine-topiramate), Wegovy (semaglutide), and Zepbound (tirzepatide). Additionally, orlistat (Xenical, Alli) is FDA-approved, with the prescription strength being Xenical and the over-the-counter version being Alli.
Here's a bit more detail on some of these:
Contrave:
This medication combines bupropion (an antidepressant) and naltrexone (used for addiction treatment) and works by suppressing appetite and affecting the brain's reward system.
Saxenda:
This is a once-daily injection that is also used to treat type 2 diabetes. It works by mimicking a hormone that regulates appetite.
Qsymia:
This medication combines phentermine (an appetite suppressant) and topiramate (an anticonvulsant). It helps reduce appetite and increase feelings of fullness.
Wegovy:
This is a higher dose of semaglutide, a GLP-1 agonist, that is specifically approved for weight loss.
Zepbound:
This medication, also a GLP-1 agonist, is a newer option for chronic weight management and is considered highly effective.
Orlistat (Xenical, Alli):
This medication works by blocking the absorption of some fat in the diet, leading to weight loss.
It is important to consult with a healthcare professional to determine if any of these medications are appropriate for your individual needs and health conditions.